McHugo GJ et al "Enhancing Validity in Co-occuring Disorders [Mentally Ill Drug Addicts] Treatment Research" Schizophrenia Bulletin Vol 32 No 4.
"Although more than 40 controlled studies show advantages for specific interventions, there have been few replications."
"The challenge before the co-occurring disorders field now is to design intervention studies that address key clinical questions in a manner that is scientifically sound and that generalize to practitioners and patients in routine practice settings."
Measuring Substance Use: "Whether the primary outcome or not, substance use will be part of any study of an intervention for co-occurring disorders. Unfortunately, there are limitations on the reliability and validity measures of substance use from any source, and the target behaviour cannot be easily measured over extended periods of time. Moreover, there are numerous possible sources of bias in verbal reports in general, many of which are likely when reporting illegal and socially undesirable behavior like drug use." (Learn more »)
"Too often, treatment nonadherence and dropout are considered nuisances rather than key outcomes, although they are among the preconditions that determine the magnitude and scope of treatment effect."
"Thus, after 20 years of research, there remains a lack of strong and clear evidence regarding effective engagement, treatment and rehabilitation interventions for people with co-occurring disorders [Mentally ill drug addicts]."
Published August 16, 2007.